HNO-Heilkunde: Open Access

Abstrakt

American Society of Pediatric Otolaryngology Genetic Testing for Vascular Malformations Patterns of Vascular Abnormalities Task Force Practise

Caroline Zeiss

Vascular anomalies can be distributed as either vascular excrescences or vascular deformations. Vascular excrescences are proliferative lesions made up of endothelial cells and vascular deformations are lesions that demonstrate abnormal vascular development and structure. The term “vascular anomalies” is used in this handwriting to capture both vascular deformations and vascular excrescences that may suffer inheritable testing. Illustration, and natural hemangiomas, which are all vascular excrescences, has also demonstrated mutations within the RAS pathway. While utmost vascular anomalies do spontaneously, some can be associated with syndromic causes, similar as Klippel- Trenaunay Pattern or Parkes Weber Syndrome. The morbidity and mortality associated with vascular anomalies is dependent on their staging and inflexibility, but can include airway inhibition and hemorrhage, facial shell overgrowth, soft towel disfiguration, pain and/ or intermittent infections