Internationale Zeitschrift für Forschung und Entwicklung in Pharmazie und Biowissenschaften

Abstrakt

ANTIDEPRESSANT ACTIVITY OF SPIRULINA PLATENSIS IN EXPERIMENTALLY INDUCED DIPRESSION IN MICE

Suresh D, Madhu M, Saritha Ch, Raj kumar V, Shankaraiah P*

The spray dried powder of Spirulina platensis was used to treatment of depression in different doses (100mg/kg, 200 mg/kg and 400 mg/kg) and Impramine (15mg/kg) as standard drug in experimental animal models like Forced swim test in mice, Tail suspension test in mice, Clonidine induced aggression behaviour in mice test, L-dopa induced hyper activity and aggressive behavior in mice, 5-HT induced head twitches in mice, From all the experimental model results were observed that the Spirulina platensis was possess the dose dependent anti depressant activity.