Zeitschrift für analytische und bioanalytische Techniken

Abstrakt

Capillary Electrophoresis (CE)

George Perry*

 Capillary electrophoresis (CE) is a family of electrokinetic separation methods performed in submillimeter diameter capillaries and in micro- and nanofluidic channels. Very often, CE refers to capillary zone electrophoresis (CZE), but other electrophoretic techniques including capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), capillary isotachophoresis and micellar electrokinetic chromatography (MEKC) belong also to this class of methods.1 In CE methods, analytes migrate through electrolyte solutions under the influence of an electric field. Analytes can be separated according to ionic mobility and/or partitioning into an alternate phase via noncovalent interactions. Additionally, analytes may be  concentrated or "focused" by means of gradients in conductivity and pH.