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Critical Appraisal of Immunity in Ayurveda

Byadgi PS

During certain conditions or factors, even unwholesome food does not produce disease immediately. The variety of unwholesome food is not equally harmful in causing disease; all dosas are not equally powerful, and variations in physique and mind play a role in resisting disease. Variances in several genes can influence how well a patient might respond to a particular drug or antigen. Resistance to disease or immunity against disease is of two kinds i.e. one that attenuates the manifested disease and the other prevents the manifestation of disease. The above concept indicates an individualistic approach in disease management. Personalized medicine is the new paradigm of modern medicine, aiming to predict the risk and treatment of disease on the basis of a person's genetic profile, which would render biologic consideration of race obsolete. But it seems unwise to abandon the practice of recording race when we have barely begun to understand the architecture of the human genome, and its implications for new strategies for the identification of gene variants that protect against, or confer susceptibility to common diseases, and modify the effects of drugs. In the international context, the concerns on personalized medicine are more obvious and advanced. It creates a new framework in terms of prompt and individualized diagnosis and treatment of the patient. Homeostasis of Ojas, agni, srotas, doshas, and dushya, along with and associated, is the pleasant state of soul, sensory organs, and mind, essential for good health. Proper use of food, sleep and celibacy is the golden triangle for excellent health. There is a great deal of synergy between Ojas, agni, srotas, doshas, and dushya; defects in either system can lead to immune-pathological disorders, including autoimmune diseases, immune-deficiencies and hypersensitivity reactions.