Internationale Zeitschrift für Forschung und Entwicklung in Pharmazie und Biowissenschaften

Abstrakt

DEVELOPMENT AND CHARACTERIZATION OF ACECLOFENAC ENTERIC COATED TABLETS

Manoj Kumar, Shiv Garg, Ashish Kumar Pareek, Sardar mal yadav, Piush Sharma

Aceclofenac is an antipyretic and antiinflammatory drug. On regular intake of Aceclofenac it may cause Ulcer and that is the major side effect of the NSAID. To protect the Ulceration the enteric coated tablets are designed. The Enteric coated tablets of Aceclofenac are designed with the Aim to provide sustained Action and prevents the drug release into stomach. The Enteric coated tablets of Aceclofenac was designed by using carriers like Xanthan gum, Carbopol, HPMC K4M. All the carrier affects the release profile of the Drug. The Enteric coating of the Formulation was carried out by using Colorcoat and Acetone. In the following research the tablet SECT2 is found as Best with the better release (99.78) than remaining all.