Klinische Infektionskrankheiten und Praxis

Abstrakt

Evolving Challenges to Immunocompromised Systemic Fungal Infections

Huang Baoying

Fungal infections throughout the planet seem to be increasing. This could partially ensue to the rise within the population of patients that square measure liable to otherwise rare plant life infections ensuing from the utilization of immune modulating procedures like biological process somatic cell transplants and medicines like tissue mortification issue antagonists. Histoplasma capsulatum, a plague plant life throughout North and South America, is reemerging among HIV+ patients in Central and South America and among patients taking tissue mortification issue antagonists and different biologics in North America. Fusarium species, a comparatively rare mycosis, is reemerging worldwide within the upset populations, particularly those that square measure neutropenic like biological process somatic cell transplant recipients. A brand new yeast species is presently rising worldwide: fungus auris, unknown simply a decade past. It inflicting giant healthcare-associated outbreaks on four continents and is spreading throughout the planet through patient travel. During this review the medicine, pathology, detection and treatment of those 3 rising and reemerging fungi are going to be mentioned.