Biotechnologie und Biomaterialien

Abstrakt

Hair Cell Regeneration: Factors and Possible Accelerators

Akanksha Sharma*

Cell regeneration is a procedure of re-development of certain dam- aged organ from its respective tissue. Cochlear is the hearing part of inner ear situated in the temporal bone. It directly interacts with middle ear through oval window and round window. Sensory cells also known as Hair cells have a cuticular plate with stereocilia bathing in the endolymph surrounding it. These are mainly of two types of Inner Hair Cells (IHC) and Outer Hair Cells (OHC). The final no. of hail cells are produced during 10 week of foetal ges- tation above this stage the cell are only loosed. Stereocilia plays an important role in electro-mechanical transduction. Myosin plays role in hearing process. During the development of mouse inner ear, cell cycle inhibitor plays an important role. Rb helps in triggering the cell cycle exit. Various factors affect the hair cells like age, genetic factors, surrounding environment etc