Magen-Darm- und Verdauungssystem

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Menetrier Disease in a Five Year Old Girl - A Case Report and Review of Literature

Virtut Velmishi, Besnik Elezi, Gentiana Cekodhima

Introduction: Menetrier`s disease is one of the rarest protein losing gastropathies in childhood characterized by hypertrophy of gastric folds. Children with Menetrier disease tend to follow a self-limited course with symptoms typically completely resolving within 2 to 10 weeks.

Case report: A five year old girl presented fever for two days, abdominal pain and vomiting. After two other days she presented periorbital swelling and skin rash. Laboratory findings on admission showed hypoalbuminemia and eosinophilia. Screening for Helicobacter pylori and cytomegalovirus resulted negative. Abdominal ultrasonography showed moderate ascitis and in chest X ray revealed effusion in both lungs. Gastroscopy showed severe erosions in fundus and in upper part of stomach body. The lower part of stomach and antrum was normal. Histopathology showed data compatible with Menetrier disease. She was treated with several albumin infusions and diuretics and her symptoms improved after 4 weeks of treatment.

Conclusion: This is the first case of pediatric MD in our experience. Endoscopic images and histological data are very important to support