Klinische Pharmakologie und Biopharmazeutik

Abstrakt

Novelty and Compliance of Oral Fast Dissolving Thin Film A Patient Friendly Dosage Form

Madiha Mushtaque, Iyad Naeem Muhmmad, Sidra Kanwal, Farah Khalid, Rida Masood, Aatka Ali

The oral fast-dissolving film is an advanced, patient compliant and novel delivery system. The acceptance of this ingenious dosage form is increasing day by day due to its several comparative advantages of being cost-benefit, rapid dissolving without water aid, as well as greatly compliant to both geriatric and pediatric patients in emergency conditions and specific diseases. Moreover, it is a worthwhile dosage form for the drug experiencing pre-systemic metabolism and lesser bioavailability. This review article covers history, advantages, disadvantages, limitations, ideal properties, classification, formulation consideration, method of manufacturing, quality parameters both in-vitro and in-vivo, advancement in technology, commercial trends and literature review of the previous work for oral fast dissolving films. It can be concluded that it one of the fastest-growing dosage forms holding a lot of potentials especially for commercial use due to its unique characteristics, novel attributes, competitive standing, and cost-adequacy.