Magen-Darm- und Verdauungssystem

Abstrakt

Rehabilitation Tool for Gastroparesis by the Analysis of Interstitial Cells of Cajal (The External Gastric Pacmaker with a Feedback of Gastric Potential)

Gokul M*, Durgadevi N, Bhuvaneshwari R, Ramya Shanmugha V and Ram Kumar C

Gastric diseases are the third most fatal to world’s population which causes substantial mortality and morbidity (nearly 60-70 million people were affected). For example: Hernia, Chronic constipation, Gastro Esophageal Reflux Disease, colorectal cancer, gastroparesis, peptic and gastric ulcers, ulcerative colitis, crohn’s disease etc. Gastroparesis (GP) is the one such disease defined as the paralysis of stomach results in delayed gastric emptying which lacks the peristaltic action of stomach that breaks down the bolus into smaller particles makes it suitable for entering into the duodenum. Gastroparesis is a condition which cannot be cured by drugs or any other therapies rather it needs a life supporting tool which grasps our attention of making innovativeness in the existing system. The reliable therapy for gastroparesis is Gastric Electrical Stimulation through enterra system. The innovation made with the our enterra system is to induce the stimulation with the feedback information from the Electrogastrograph (EGG) module that enables the pacemaker to work on synchronous mode rather than the existing enterra system that induce the stimulation with the help of timing and clock circuit or activated by the patients. The EGG that extracts the functional information of stomach is solely being the appropriate and effective method to study motility parameter to establish gastric pacing activity. The best solution for this most intolerable disease can be provided by the gastric electrical stimulation of the Interstitial Cells of Cajal (ICC) called pacemaker.