Zeitschrift für klinische und experimentelle Pathologie

Abstrakt

Macrophage Subtypes, Phenotypes, Inflammatory Molecules, Cytokines, and Atherosclerotic Lesions: Atherosclerosis, Metabolic Diseases and Pathogenesis, the Therapeutic Challenges

Rajiv Kumar, Mitrabasu Chhillar

Macrophages, the phagocytes are considered the main cause for atherosclerosis, and any change or alteration in their dynamics is identified as the foremost cause for the development of atherosclerotic plaque microenvironment. These biophysical changes stimulus the defenselessness or steadiness of progressive atherosclerotic lesions and promote the route of plaque progression.